There's been a lot of news, some of it fear-mongering, about Pfizer's Covid drug Paxlovid. Some people are having their symptoms return after completing the five-day course. Does that mean there is something wrong with the drug, or it's simply a property of the virus? Drs. Henry Miller and Josh Bloom try to provide an answer in Issues & Insights.
A recent study showed that Pfizer's Paxlovid, the most effective Covid drug, failed to prevent infection when given to people who were exposed to the virus but had not yet become infected. Bad news, right? Actually, no - it's quite the opposite. Here's why.
President Eisenhower worried that we were creating a scientific/technologic elite that controls the narrative and stifles heterodoxy. But the digital age and the democratization of knowledge threaten the scientific "priesthood" – much in the way the printing press threatened the controlling interest of an earlier time. The priesthood must learn to adapt to a world where it no longer has a monopoly on specialized knowledge.
Dr. Fauci, along with two of his colleagues, writes in a journal on the concept of herd immunity and COVID-19. Buckle up; it will be a bumpy ride, at least in the media.
Should the COVID drug Paxlovid be available without a prescription? Some argue that pharmacists should be able to distribute the drug to people who have tested positive for COVID while others, including the AMA, believe that only physicians should be able to prescribe the drug because of some potentially dangerous drug-drug interactions. Cato Institute's Dr. Jeffrey Singer weighs in.
Canada has approved Medicago's plant-based COVID-19 vaccine. The new shot itself is an impressive development, but the technology it's built on suggests that we may be growing more drugs in greenhouses in the coming years.
There’s considerable discussion about whether COVID vaccines are responsible for the barrage of variants that keep hitting us. Is selective pressure driving this – like with bacteria and antibiotics? Let's take a look.
An unexpected delay in the FDA's authorization of COVID shots for children under age 5 could amplify parents' existing concerns about vaccinating their kids. Here's what we know about the situation.
We continue to be awash with COVID stories. But let us cut to the chase. How many annual COVID-19 deaths are the nation prepared to tolerate on a routine basis? Substantial public health efforts have been devoted to reducing these other causes of death; why should COVID be different? Reducing traffic accident deaths by mandating vehicle seat belts comes to mind, for which some 9000 lives were saved each year. How prepared are we to similarly enforce a comprehensive COVID-19 vaccination program?
The published literature on COVID now exceeds 211,000 papers, books, and documents, which include: 22,866 observational studies, 19,591 reviews, 1496 meta-analyses and 781 randomized control trials. These publications comprise the backdrop for our research and writing. The project began in the spring of 2020 based on a limited source of cumulative COVID-19 data and has broadened considerably. Here is what we have learned.
The same mRNA technology that gave us effective COVID-19 vaccines could yield a new generation of highly protective seasonal flu shots. When will we see these upgraded influenza vaccines? Perhaps sooner than you think.
In a bid to bolster their flagging anti-biotech agenda, several high-profile activist groups have bizarrely joined the chorus of voices suggesting that SARS-CoV-2 escaped from a lab. The science community needs to make clear that wherever the virus came from, its beginnings do not undermine the safety or efficacy of important biotechnology innovations in food and medicine.